Négra Lock (French: écluse de Négra) is a single chamber lock on the Canal du Midi near the village of Villefranche-de-Lauragais in Languedoc, France. There is a small chapel at the lock and also a small red-brick aqueduct which carries the canal over the Thésauque, a tributary of the Hers. Négra Lock is at an altitude of 166m and is ascending when travelling west–east. The adjacent locks are to the east and to the west.