Natalie Griffin de Blois (April 2, 1921 – July 22, 2013) was an American architect. She began her architectural career in 1944 and became known as a pioneer in the male-dominated world of architecture. She was a partner for many years in the firm of Skidmore, Owings and Merrill" Her notable works include the Pepsi Cola Headquarters, Lever House, and the Union Carbide Building in New York City, the Equitable Building in Chicago, the low-rise portions of the Ford World Headquarters in Dearborn, Michigan, and the Connecticut General Life Insurance Company Headquarters in Bloomfield, Connecticut. Several of de Blois' buildings are included in the tallest woman-designed buildings in the world. She later taught architecture at the University of Texas in the 1980s and 1990s.