State Route 338 (SR 338) was a state highway in the southeastern portion of the U.S. state of Ohio, entirely in Meigs County. Running along the Ohio River, the route existed from 1932 until about 2012. For most of its history, SR 338 ran along the river between Racine and Lebanon Township with both ends at SR 124. At the time of its removal from the state highway system, the last remnant of the route was a 2.3-mile-long (3.7 km) segment (designated by the Ohio Department of Transportation (ODOT) as SR 338-J) between US 33 near the Ravenswood Bridge and SR 124.