Oligonucleotide synthesis
Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical oligonucleotide synthesis does not have this limitation, although it is most often carried out in the opposite, 3' to 5' direction. Currently, the process is implemented as solid-phase synthesis using phosphoramidite method and phosphoramidite building blocks derived from protected 2'-deoxynucleosides (dA, dC, dG, and T), ribonucleosides (A, C, G, and U), or chemically modified nucleosides, e.g. LNA or
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Oligonucleotide synthesis
Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure (sequence). The technique is extremely useful in current laboratory practice because it provides a rapid and inexpensive access to custom-made oligonucleotides of the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5' to 3' direction, chemical oligonucleotide synthesis does not have this limitation, although it is most often carried out in the opposite, 3' to 5' direction. Currently, the process is implemented as solid-phase synthesis using phosphoramidite method and phosphoramidite building blocks derived from protected 2'-deoxynucleosides (dA, dC, dG, and T), ribonucleosides (A, C, G, and U), or chemically modified nucleosides, e.g. LNA or
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Chemiczna synteza oligonukleot ...... tydy znajdują zastosowanie w .
@pl
La synthèse d'oligonucléotide ...... ue avec une structure définie.
@fr
La síntesis de oligonucleótido ...... síntesis artificial de genes.
@es
Oligonucleotide synthesis is t ...... synthesis of artificial genes.
@en
Синтез олигонуклеотидов — это ...... я синтеза искусственных генов.
@ru
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Chemiczna synteza oligonukleot ...... ekwencji zasad nukleotydowych.
@pl
La synthèse d'oligonucléotide ...... ue avec une structure définie.
@fr
La síntesis de oligonucleótido ...... nte modificados, como los ANB.
@es
Oligonucleotide synthesis is t ...... fied nucleosides, e.g. LNA or
@en
Синтез олигонуклеотидов — это ...... помощи электрофореза или ВЭЖХ.
@ru
label
Chemiczna synteza oligonukleotydów
@pl
Oligonucleotide synthesis
@en
Synthèse d'oligonucléotide
@fr
Síntesis de oligonucleótidos
@es
Синтез олигонуклеотидов
@ru