Oseltamivir total synthesis
Oseltamivir total synthesis concerns the total synthesis of the antiinfluenza drug oseltamivir marketed by Hoffmann-La Roche under the trade name Tamiflu. Its commercial production starts from the biomolecule shikimic acid harvested from Chinese star anise with a limited worldwide supply. Due to its limited supply, searches for alternative synthetic routes preferably not requiring shikimic acid are underway and to date several such routes have been published. Control of stereochemistry is important: the molecule has three stereocenters and the sought-after isomer is only 1 of 8 stereoisomers.
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Oseltamivir total synthesis
Oseltamivir total synthesis concerns the total synthesis of the antiinfluenza drug oseltamivir marketed by Hoffmann-La Roche under the trade name Tamiflu. Its commercial production starts from the biomolecule shikimic acid harvested from Chinese star anise with a limited worldwide supply. Due to its limited supply, searches for alternative synthetic routes preferably not requiring shikimic acid are underway and to date several such routes have been published. Control of stereochemistry is important: the molecule has three stereocenters and the sought-after isomer is only 1 of 8 stereoisomers.
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La synthèse totale de l'oselta ...... es 8 stéréoisomères possibles.
@fr
La síntesis total del oseltami ...... os 8 posibles estereoisómeros.
@es
Oseltamivir total synthesis co ...... is only 1 of 8 stereoisomers.
@en
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La synthèse totale de l'oselta ...... es 8 stéréoisomères possibles.
@fr
La síntesis total del oseltami ...... os 8 posibles estereoisómeros.
@es
Oseltamivir total synthesis co ...... is only 1 of 8 stereoisomers.
@en
label
Oseltamivir total synthesis
@en
Synthèse totale de l'oseltamivir
@fr
Síntesis total del oseltamivir
@es