PNU-99,194
PNU-99,194(A) (or U-99,194(A)) is a drug which acts as a moderately selective D3 receptor antagonist with ~15-30-fold preference for D3 over the D2 subtype. Though it has substantially greater preference for D3 over D2, the latter receptor does still play some role in its effects, as evidenced by the fact that PNU-99,194 weakly stimulates both prolactin secretion and striatal dopamine synthesis, actions it does not share with the more selective (100-fold) D3 receptor antagonists and .
PNU-99,194-APNU-99,194APNU-99194PNU-99194-APNU-99194APNU99,194PNU99,194-APNU99,194APNU99194PNU99194-APNU99194APNU 99,194-APNU 99,194APNU 99,194 APNU 99194-APNU 99194APNU 99194 AU-99,194U-99,194-AU-99,194AU-99194U-99194AU99,194AU99194U99194AU 99,194U 99,194-AU 99,194AU 99,194 AU 99194U 99194AU 99194 A
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2-AminoindaneC17H27NO2Dopamine receptor D3List of dopaminergic drugsPNU-99,194-APNU-99,194APNU-99194PNU-99194-APNU-99194APNU99,194PNU99,194-APNU99,194APNU99194PNU99194-APNU99194APNU 99,194-APNU 99,194APNU 99,194 APNU 99194-APNU 99194APNU 99194 AU-99,194U-99,194-AU-99,194AU-99194U-99194AU99,194AU99194U99194AUH-232U 99,194U 99,194-AU 99,194AU 99,194 AU 99194U 99194AU 99194 A
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PNU-99,194
PNU-99,194(A) (or U-99,194(A)) is a drug which acts as a moderately selective D3 receptor antagonist with ~15-30-fold preference for D3 over the D2 subtype. Though it has substantially greater preference for D3 over D2, the latter receptor does still play some role in its effects, as evidenced by the fact that PNU-99,194 weakly stimulates both prolactin secretion and striatal dopamine synthesis, actions it does not share with the more selective (100-fold) D3 receptor antagonists and .
has abstract
PNU-99,194(A) (or U-99,194(A)) ...... aine in both rats and monkeys.
@en
CAS number
(hydrochloride)
82668-33-5
ChEMBL
FDA UNII code
929J96FO8T
PubChem
Wikipage page ID
27,160,424
page length (characters) of wiki page
Wikipage revision ID
1,015,312,145
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ATC prefix
none
@en
CAS number
ChEMBL
ChemSpiderID
IUPAC name
legal status
Uncontrolled
@en
PubChem
routes of administration
SMILES
OC
@en
wikiPageUsesTemplate
hypernym
comment
PNU-99,194(A) (or U-99,194(A)) ...... D3 receptor antagonists and .
@en
label
PNU-99,194
@en