Pegaptanib
Pegaptanib sodium injection (brand name Macugen) is an anti-angiogenic medicine for the treatment of neovascular (wet) age-related macular degeneration (AMD). It was discovered by (which merged with Gilead Sciences in 1999) and licensed in 2000 to EyeTech Pharmaceuticals, now OSI Pharmaceuticals, for late stage development and marketing in the United States. Gilead Sciences continues to receive royalties from the drugs licensing. Outside the US pegaptanib is marketed by Pfizer. Approval was granted by the U.S. Food and Drug Administration (FDA) in December 2004.
product
ATC code S01ATC code S01LA03ATCvet code QS01LA03Anti–vascular endothelial growth factor therapyAptamerAstellas PharmaC294H342F13N107Na28O188P28Central retinal vein occlusionChoroidal neovascularizationCorneal neovascularizationDavid L. HallalGilead_SciencesIntravitreal injectionJoan MillerList of drugs: Pb–PeMacugenMacular degenerationMacular edemaMucagenOSI PharmaceuticalsPEGylationPegabtanibPegaptanib sodiumProtein kinase inhibitorRNA therapeuticsRetinopathySystematic evolution of ligands by exponential enrichmentVascular endothelial growth factor
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primaryTopic
Pegaptanib
Pegaptanib sodium injection (brand name Macugen) is an anti-angiogenic medicine for the treatment of neovascular (wet) age-related macular degeneration (AMD). It was discovered by (which merged with Gilead Sciences in 1999) and licensed in 2000 to EyeTech Pharmaceuticals, now OSI Pharmaceuticals, for late stage development and marketing in the United States. Gilead Sciences continues to receive royalties from the drugs licensing. Outside the US pegaptanib is marketed by Pfizer. Approval was granted by the U.S. Food and Drug Administration (FDA) in December 2004.
has abstract
Pegaptanib (łac. pegaptanibbum ...... ej związanego z wiekiem (AMD).
@pl
Pegaptanib es un medicamento d ...... aquejados de esta enfermedad.
@es
Pegaptanib sodium injection (b ...... ration (FDA) in December 2004.
@en
ペガプタニブナトリウム（Pegaptanib sodium） ...... 8年7月には日本でも承認された。日本初の「核酸医薬」である。
@ja
alternative name
Macugen
@en
CAS number
222716-86-1
chemical formula
C294H342F13N107Na28O188P28[C2H4O](m+n) (m+n≈900)
DrugBank
FDA UNII code
2H1PA8H1EN
MedlinePlus
Wikipage page ID
page length (characters) of wiki page
Wikipage revision ID
992,188,419
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ATC prefix
S01
@en
ATC suffix
LA03
@en
CAS number
chemical formula
C294H342F13N107Na28O188P28[C2H4O]
@en
ChemSpiderID
none
@en
drug name
Pegaptanib sodium
@en
DrugBank
DB04895
@en
elimination half-life
IUPAC name
RNA, , 5'-ester with α,α'-[4,1 ...... is[ω-methoxypoly], sodium salt
@en
legal US
Rx-only
@en
MedlinePlus
a607057
@en
molecular weight
~50 kg/mol
@en
pregnancy US
B
@en
routes of administration
Intravitreal injection
@en
tradename
Macugen
@en
verifiedrevid
464,197,562
Watchedfields
changed
@en
wikiPageUsesTemplate
hypernym
comment
Pegaptanib (łac. pegaptanibbum ...... ej związanego z wiekiem (AMD).
@pl
Pegaptanib es un medicamento d ...... aquejados de esta enfermedad.
@es
Pegaptanib sodium injection (b ...... ration (FDA) in December 2004.
@en
ペガプタニブナトリウム（Pegaptanib sodium） ...... 8年7月には日本でも承認された。日本初の「核酸医薬」である。
@ja
label
Pegaptanib
@de
Pegaptanib
@en
Pegaptanib
@es
Pegaptanib
@pl
ペガプタニブ
@ja
sameAs
wasDerivedFrom
isPrimaryTopicOf
name
Pegaptanib sodium
@en