Progress M-16 (Russian: Прогресс М-16) was a Russian uncrewed cargo spacecraft which was launched in 1993 to resupply the Mir space station. The thirty-fourth of sixty-four Progress spacecraft to visit Mir, it used the Progress-M 11F615A55 configuration, and had the serial number 216. It carried supplies including food, water and oxygen for the EO-13 crew aboard Mir, as well as equipment for conducting scientific research, and fuel for adjusting the station's orbit and performing manoeuvres.