Pusticamica Lake is a freshwater body of the southeastern portion of Eeyou Istchee James Bay (municipality), in Jamésie, in the administrative region of Nord-du-Québec, in the province of Quebec, in Canada. This body of water extends into the townships of Duplessis, Mountain, Benoit and Ruette. Forestry is the main economic activity of the sector. Recreational tourism activities come second. The surface of Pusticamica Lake is usually frozen from early November to mid-May, however, safe ice movement is generally from mid-November to mid-April.