RTIOX-276
RTIOX-276 is an orexin antagonist. RTIOX-276 binds selectively to the Orexin 1 receptor (KE = 8.5nM) and lacks significant affinity for the Orexin 2 receptor (KE = > 10,000nM). RTIOX-276 may have therapeutic utility for the treatment of cocaine addiction. In conditioned place preference studies, RTIOX-276 attenuated the development of place preference in mice exposed to cocaine.
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RTIOX-276
RTIOX-276 is an orexin antagonist. RTIOX-276 binds selectively to the Orexin 1 receptor (KE = 8.5nM) and lacks significant affinity for the Orexin 2 receptor (KE = > 10,000nM). RTIOX-276 may have therapeutic utility for the treatment of cocaine addiction. In conditioned place preference studies, RTIOX-276 attenuated the development of place preference in mice exposed to cocaine.
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RTIOX-276 is an orexin antagon ...... ce in mice exposed to cocaine.
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O=CCN2CC4=CC=CC=C4CC2
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RTIOX-276 is an orexin antagon ...... ce in mice exposed to cocaine.
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RTIOX-276
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