Rafael Moreno Valle (August 13, 1917 – February 13, 2016) was a Mexican military physician and politician. A member of PRI, he served as the Governor of Puebla from 1969 to 1974, as well as the Secretary of Health from 1964 to 1968 under President Gustavo Díaz Ordaz. He was also a founding member of the Sociedad Mexicana de Traumatología y Ortopedia. Moreno was the grandfather of Rafael Moreno Valle Rosas, who has served as the Governor of Puebla since 2011.