Reptynub (/rɛptiːnʊb/; also written as Repytnub and Reputnebu) was a Queen during the Fifth Dynasty of Egypt. She was the wife of King Nyuserre Ini. She was possibly a mother of Menkauhor Kaiu (if he was Nyuserre’s son). Reptynub is identified as the wife of Nyuserre based on the discovery of a fragment of a statue in his mortuary temple. A smaller pyramid next to that of Nyuserre likely belonged to his wife and the pyramid may have belonged to Reptynub. Another probable child of Reptynub was Prince Khentykauhor.