Safiye Ali (2 February 1894 – 5 July 1952) was a Turkish physician, the first female medical doctor of the Republic of Turkey. She was a graduate of Robert College in Istanbul. She treated soldiers in the Balkan Wars, World War I, and the Turkish War of Independence. She studied medicine in Germany in 1916 and opened her office in Istanbul in 1923. Her name has been given to a family health center in Istanbul. She has done major research on the welfare of mothers and infants. With the lessons she provided to female students, she also made history as the first woman to teach medicine.