Small nucleolar RNA SNORA74
Small nucleolar RNA SNORA74 (U19) belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, and in the case of the H/ACA class) to form snoRNP complexes. This class is thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs. Targets may include ribosomal and spliceosomal RNAs but the exact functions of many snoRNAs, including U19, are not confirmed. Co-precipitation of U19 snoRNA with RNase MRP RNA suggests that U19 may be involved in pre-rRNA processing.
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Small nucleolar RNA SNORA74
Small nucleolar RNA SNORA74 (U19) belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, and in the case of the H/ACA class) to form snoRNP complexes. This class is thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs. Targets may include ribosomal and spliceosomal RNAs but the exact functions of many snoRNAs, including U19, are not confirmed. Co-precipitation of U19 snoRNA with RNase MRP RNA suggests that U19 may be involved in pre-rRNA processing.
has abstract
Small nucleolar RNA SNORA74 (U ...... volved in pre-rRNA processing.
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Wikipage page ID
11,421,873
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992,441,147
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AltSymbols
U19
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caption
Predicted secondary structure and sequence conservation of SNORA74
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id
RF00090
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name
Small nucleolar RNA SNORA74
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Rfam
RF00090
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RNA type
Gene; snRNA; snoRNA; H/ACA-box
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symbol
SNORA74
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Tax domain
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comment
Small nucleolar RNA SNORA74 (U ...... volved in pre-rRNA processing.
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label
Small nucleolar RNA SNORA74
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