St. Mary's Medical Center may refer to: * St. Mary's Medical Center (San Francisco), San Francisco, California * , West Palm Beach, Florida * , Blue Springs, Missouri * , Knoxville, Tennessee * St. Mary's Medical Center (Huntington), Huntington, West Virginia * St. Mary's of Michigan Medical Center, Saginaw, Michigan * St. Mary's Hospital Medical Center, Green Bay, Wisconsin * St. Mary's Hospital and Medical Center, Evansville, Indiana * , Duluth, Minnesota * , Clearwater, Florida * St. Mary's Medical Center (Grand Junction, Colorado)