Sylvia Trent-Adams (born circa 1965) is a retired U.S. Public Health Service Commissioned Corps rear admiral, who last served as the principal deputy assistant secretary for health from January 2, 2019 to August 31, 2020. She previously served as the deputy surgeon general of the United States from October 25, 2015 to January 2, 2019. Trent-Adams also served as the acting surgeon general of the United States from April 21, 2017 to September 5, 2017. She retired from the U.S. Public Health Service on September 30, 2020 after over 33 years of combined uniformed service. On October 5, 2020, Trent-Adams was named to the board of directors for AMN Healthcare.