The Siege of Damascus is a 1720 tragedy by the British writer John Hughes. It was inspired by Simon Ockley's 1708 study Conquest of Syria, and focuses specifically on the Siege of Damascus in 634. Originally staged at the Theatre Royal, Drury Lane, with Thomas Walker, Barton Booth, John Mills, Mary Porter and John Thurmond in the cast, it was a success and was revived frequently in the eighteenth century. It was his final work as he died shortly after its premiere.