Tynorphin
Tynorphin is a synthetic opioid peptide which is a potent and competitive inhibitor of the enkephalinase class of enzymes which break down the endogenous enkephalin peptides. It specifically inactivates dipeptidyl aminopeptidase III (DPP3) with very high efficacy, but also inhibits neutral endopeptidase (NEP), aminopeptidase N (APN), and angiotensin-converting enzyme (ACE) to a lesser extent. It has a pentapeptide structure with the amino acid sequence Val-Val-Tyr-Pro-Trp. Tynorphin was discovered in an attempt to develop an enkephalinase inhibitor of greater potency than spinorphin.
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Tynorphin
Tynorphin is a synthetic opioid peptide which is a potent and competitive inhibitor of the enkephalinase class of enzymes which break down the endogenous enkephalin peptides. It specifically inactivates dipeptidyl aminopeptidase III (DPP3) with very high efficacy, but also inhibits neutral endopeptidase (NEP), aminopeptidase N (APN), and angiotensin-converting enzyme (ACE) to a lesser extent. It has a pentapeptide structure with the amino acid sequence Val-Val-Tyr-Pro-Trp. Tynorphin was discovered in an attempt to develop an enkephalinase inhibitor of greater potency than spinorphin.
has abstract
Tynorphin is a synthetic opioi ...... eater potency than spinorphin.
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PubChem
Wikipage page ID
33,863,120
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Wikipage revision ID
1,020,298,394
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ATC prefix
None
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ChemSpiderID
IUPAC name
(-2-(2S)-1-[(2S)-2-[[(2S)-2-[[ ...... (1H-indol-3-yl)propanoic acid)
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legal status
Non-regulated
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PubChem
SMILES
CC[C@@H]N
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O=C[C@@H]CC
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StdInChIKey
WLWBANYDSJWZBI-IIZANFQQSA-N
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wikiPageUsesTemplate
hypernym
comment
Tynorphin is a synthetic opioi ...... eater potency than spinorphin.
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label
Tynorphin
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