Werner syndrome helicase
Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. WRN is a member of the RecQ Helicase family. Helicase enzymes generally unwind and separate double-stranded DNA. These activities are necessary before DNA can be copied in preparation for cell division (DNA replication). Helicase enzymes are also critical for making a blueprint of a gene for protein production, a process called transcription. Further evidence suggests that Werner protein plays a critical role in repairing DNA. Overall, this protein helps maintain the structure and integrity of a person's DNA.
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Bloom syndrome1,2-dimethoxyethaanCancer syndromeChromosome 8DNA-PKcsDNA damage theory of agingDNA methylation in cancerDNA repair-deficiency disorderDrosophila melanogasterEvolution of ageingExtrachromosomal rDNA circleFlap structure-specific endonuclease 1G-quadruplexGenome instabilityHelicaseHistone acetyltransferaseHomologous recombinationIntravascular lymphomasKu70Ku80List of OMIM disorder codesList of human protein-coding genes 4Malignant transformationNeoplasmNon-small-cell lung carcinoma1,2-dimethoxyethaanPARP1POLD1Progeroid syndromes1,2-dimethoxyethaanRECQ3RECQL2RecQ helicaseRecq3Recql2Sirtuin 1Somatic evolution in cancerSp1 transcription factorSynthetic lethalityTERF2
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Werner syndrome helicase
Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. WRN is a member of the RecQ Helicase family. Helicase enzymes generally unwind and separate double-stranded DNA. These activities are necessary before DNA can be copied in preparation for cell division (DNA replication). Helicase enzymes are also critical for making a blueprint of a gene for protein production, a process called transcription. Further evidence suggests that Werner protein plays a critical role in repairing DNA. Overall, this protein helps maintain the structure and integrity of a person's DNA.
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Werner syndrome ATP-dependent ...... 0,319 to base pair 31,150,818.
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Werner syndrome ATP-dependent ...... d integrity of a person's DNA.
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Werner syndrome helicase
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