When in Love is the first single from MC Lyte's third album Act Like You Know. It was released on August 22, 1991. Although its original version of the album is produced by Wolf & Epic, its single version includes a remix made with Carmen Rizzo. The song presents a style more oriented to the New Jack Swing sound. In November 1991, the song peaked No. 14 on the Billboard's Hot R&B Singles, where it remained for 13 weeks, being his most successful song on that list to that date. Also peaking at No. 3 on the Billboard Hot Rap Singles.