William Ayshford Sanford, DL (1818– 28 October 1902) was a landowner, naturalist and Liberal Party politician, who served as Colonial Secretary of Western Australia from 1852 to 1855. Sanford was born in 1818, the son of Edward Ayshford Sanford, a Member of Parliament for Somerset, by his first wife Henrietta Langham, daughter of Sir William Langham, 8th Baronet. The family had owned Nynehead Court in Somerset since 1599, and William Ayshford Sanford succeeded to the estate on the death of his father in 1871. Sanford died at his residence Nynehead Court, Somerset, on 28 October 1902.