Sir William Handcock (11 September 1654 – September 1701) was an Irish politician and judge. Born in County Westmeath, he was the second son of William Handcock and his wife Abigail, daughter of Sir Thomas Stanley and Mary Hammond, and sister of Thomas Stanley. His older brother was Thomas Handcock. He was educated at Trinity College, Dublin. Handcock entered the Irish House of Commons in 1692, representing Boyle until the following year. He sat for Dublin City from 1695 until 1699. Handcock was appointed Recorder of Dublin in 1695, a post he held until his death in 1701.