William F. Rose (September 16, 1909 – May 29, 1972) was an American illustrator and film poster artist active in the 1930s and 1940s. He is recognized as one of the most distinctive poster artists of the Classical Hollywood era, a time when most film posters featured painted illustrations rather than photography. Rose painted dozens of poster illustrations for RKO Radio Pictures and other studios. As one of the leading designers in RKO's art department, he helped to define the studio's bold visual aesthetic. Although he was prolific, only a fraction of his poster designs have been individually attributed to him. Most of his output remains unidentified. His artwork is prized by collectors, and original prints of his posters have fetched high prices at auction.