Zinc uptake regulator
The zinc uptake regulator (Zur) gene is a bacterial gene that codes for a transcription factor protein involved in zinc homeostasis. The protein is a member of the ferric uptake regulator family and binds zinc with high affinity. It typically functions as a repressor of zinc uptake proteins via binding to characteristic promoter DNA sequences in a dimer-of-dimers arrangement that creates strong cooperativity. Under conditions of zinc deficiency, the protein undergoes a conformational change that prevents DNA binding, thereby lifting the repression and causing zinc uptake genes such as ZinT and the ZnuABC zinc transporter to be expressed.
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Zinc uptake regulator
The zinc uptake regulator (Zur) gene is a bacterial gene that codes for a transcription factor protein involved in zinc homeostasis. The protein is a member of the ferric uptake regulator family and binds zinc with high affinity. It typically functions as a repressor of zinc uptake proteins via binding to characteristic promoter DNA sequences in a dimer-of-dimers arrangement that creates strong cooperativity. Under conditions of zinc deficiency, the protein undergoes a conformational change that prevents DNA binding, thereby lifting the repression and causing zinc uptake genes such as ZinT and the ZnuABC zinc transporter to be expressed.
has abstract
The zinc uptake regulator (Zur ...... c transporter to be expressed.
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49,359,017
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1,021,814,452
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caption
The E. coli Zur protein in a d ...... nd zinc ions . Rendered from .
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name
Zinc uptake regulation protein
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Organism
Escherichia coli
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symbol
Zur
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UniProt
P0AC51
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hypernym
type
comment
The zinc uptake regulator (Zur ...... c transporter to be expressed.
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label
Zinc uptake regulator
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