"Big Man on Hippocampus" is the tenth episode of the eighth season of the American animated sitcom Family Guy. It originally aired on Fox in the United States on January 3, 2010. The episode features Peter after he suddenly begins suffering from amnesia, and can no longer remember anything about his life, including his own family and friends. His wife, Lois, then attempts to reintroduce Peter to his surroundings, but he soon discovers partying, and having sex with other women is much more entertaining. Frustrated, Lois decides to leave her husband, causing her neighbor, Quagmire, to attempt to win her over.