The 1917 Detroit Titans football team represented the University of Detroit in the 1917 college football season. Detroit outscored opponents by a combined total of 389 to 34 and finished with an 8–1 record in their first year under head coach James F. Duffy. The Titans opened the season with a school record 145 to 0 victory over the Toledo Rockets. In the second game of the season, Detroit lost to the 1917 Michigan Wolverines football team by a 14 to 3 score. The team won its final seven games, including a 14 to 0 victory over Michigan State. Tillie Voss starred for the 1917 team.