The 1935 Michigan State Spartans football team represented Michigan State College in the 1935 college football season. In their third season under head coach Charlie Bachman, the Spartans compiled a 6–2 record and won their annual rivalry game with Michigan by a 25 to 6 score. In inter-sectional play, the team defeated Kansas (42-0) and Loyola Marymount (27-0) but lost to Boston College (18-6). Guard Sid Wagner was a consensus first-team player on the 1935 College Football All-America Team.