The 1995 Michigan State Spartans football team competed on behalf of Michigan State University in the Big Ten Conference during the 1995 NCAA Division I-A football season. Head coach Nick Saban was in his first season with the Spartans. Michigan State played their home games at Spartan Stadium in East Lansing, Michigan. The Spartans went 6–4–1 overall and 4–3–1 in conference play during the regular season. The team played in the Independence Bowl on December 29, 1995 and were defeated 45–26 by Saban's future employer, LSU.