The 2001 MainStay Independence Bowl, part of the 2001–02 bowl game season, took place on December 27, 2001, at Independence Stadium in Shreveport, Louisiana. The competing teams were the Alabama Crimson Tide, representing the Southeastern Conference (SEC), and the Iowa State Cyclones of the Big 12 Conference (Big 12). Alabama won the game, 14–13 in what was the first all-time game between the programs. It was also the first bowl game for Dennis Franchione at Alabama and the second bowl game for Dan McCarney at Iowa State.