7-PET
7-PET was discovered by K.W. Bentley and is a potent opioid analgesic drug, 300 times the potency of morphine by weight. It is related to the more well-known oripavine derivative opioid etorphine, which is used as a very potent veterinary painkiller and anesthetic medication, used primarily for the sedation of large animals such as elephants, giraffes and rhinos. 7-PET itself has a 3-O-methyl ether which reduces potency, but the 3-OH derivative is around 2200x morphine, almost the same potency as etorphine as a μ agonist, and unexpectedly the 3-desoxy compound is also around the same potency of 2000x morphine.
7-PET
7-PET was discovered by K.W. Bentley and is a potent opioid analgesic drug, 300 times the potency of morphine by weight. It is related to the more well-known oripavine derivative opioid etorphine, which is used as a very potent veterinary painkiller and anesthetic medication, used primarily for the sedation of large animals such as elephants, giraffes and rhinos. 7-PET itself has a 3-O-methyl ether which reduces potency, but the 3-OH derivative is around 2200x morphine, almost the same potency as etorphine as a μ agonist, and unexpectedly the 3-desoxy compound is also around the same potency of 2000x morphine.
has abstract
7-PET was discovered by K.W. B ...... da, Australia and New Zealand.
@en
CAS number
13965-63-4
IUPAC name
(2R)-2-((4R,7S,7aR,12bS,14R)-7 ...... olin-14-yl)-4-phenylbutan-2-ol
@en
PubChem
thumbnail
Wikipage page ID
13,967,202
Wikipage revision ID
725,354,198
ChemSpiderID
21,106,246
smiles
O[C@][C@H]7CC64\C=C/[C@@]7[C@@H]5Oc2c3cC[C@H]6NC
StdInChIKey
CSZMZMPPNJFGRW-TZBHJBKBSA-N
Verifiedfields
verifiedrevid
477,226,838
Watchedfields
hypernym
comment
7-PET was discovered by K.W. B ...... ame potency of 2000x morphine.
@en
label
7-PET
@en