Alpha 1-antitrypsin deficiency
Alpha 1-antitrypsin deficiency (α1-antitrypsin deficiency, A1AD) is a genetic disorder that causes defective production of alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells. There are several forms and degrees of deficiency; the form and degree depend on whether the sufferer has one or two copies of a defective allele. In the literature it has been described as either a recessive or co-dominant trait as there is some evidence that smoking heterozygotes are affected. Severe A1AT deficiency causes panacinar emphysema or COPD in adult life in many people with the condition (especially if they are exposed to cigarette smoke). The disorder can lead to various liver diseases in a minority of chi
death cause
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A1ADA1 antitrypsin deficiencyA1adAlpha-1-Antitrypsin DeficiencyAlpha-1-antitrypsin deficiencyAlpha-1 antitrypsin deficiencyAlpha-1 proteinase inhibitorAlpha-1 related emphysemaAlpha 1 anti-trypsin deficiencyAlpha 1 antitrypsin deficiencyFamilial emphysemaΑ-1 antitrypsin deficiencyΑ-Antitrypsin deficiencyΑ1-Antitrypsin deficiencyΑ1-antitrypsin deficiencyΑ1 antitrypsin deficiency
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Alpha 1-antitrypsin deficiency
Alpha 1-antitrypsin deficiency (α1-antitrypsin deficiency, A1AD) is a genetic disorder that causes defective production of alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells. There are several forms and degrees of deficiency; the form and degree depend on whether the sufferer has one or two copies of a defective allele. In the literature it has been described as either a recessive or co-dominant trait as there is some evidence that smoking heterozygotes are affected. Severe A1AT deficiency causes panacinar emphysema or COPD in adult life in many people with the condition (especially if they are exposed to cigarette smoke). The disorder can lead to various liver diseases in a minority of chi
has abstract
25بك المحتوى هنا ينقصه الاستشه ...... رة طويلة وقد تدوم طيلة حياتهم.
@ar
A deficiência de alfa-1 antitr ...... pulmonar obstrutiva crônica).
@pt
Alfa-1-antitrypsinedeficiëntie ...... traveneuze aanvulling van AAT.
@nl
Alpha 1-antitrypsin deficiency ...... y and reduces life expectancy.
@en
Der α1-Antitrypsin-Mangel (Syn ...... ose und Lungenemphysem führen.
@de
Il deficit di alfa-1-antitrips ...... spondono alle normali terapie.
@it
La deficiencia de alfa-1 antit ...... s, como el humo de cigarrillo.
@es
Le déficit en alpha 1-antitryp ...... ns cas, une maladie hépatique.
@fr
α1-antytrypsyna jest białkiem ...... ółtej i czarnej jest mniejsza.
@pl
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Structure of Alpha 1-antitrypsin
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Alpha1-Antitrypsin Deficiency
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25بك المحتوى هنا ينقصه الاستشه ...... رة طويلة وقد تدوم طيلة حياتهم.
@ar
A deficiência de alfa-1 antitr ...... pulmonar obstrutiva crônica).
@pt
Alfa-1-antitrypsinedeficiëntie ...... lde huidziekte (panniculitis).
@nl
Alpha 1-antitrypsin deficiency ...... diseases in a minority of chi
@en
Der α1-Antitrypsin-Mangel (Syn ...... ose und Lungenemphysem führen.
@de
Il deficit di alfa-1-antitrips ...... epatici nei soggetti giovani.
@it
La deficiencia de alfa-1 antit ...... s, como el humo de cigarrillo.
@es
Le déficit en alpha 1-antitryp ...... ns cas, une maladie hépatique.
@fr
α1-antytrypsyna jest białkiem ...... ółtej i czarnej jest mniejsza.
@pl
label
Alfa-1-antitrypsinedeficiëntie
@nl
Alpha 1-antitrypsin deficiency
@en
Alpha-1-Antitrypsin-Mangel
@de
Deficiencia de alfa-1 antitripsina
@es
Deficit di alfa 1-antitripsina
@it
Deficiência de alfa-1-antitripsina
@pt
Déficit en alpha 1-antitrypsine
@fr
Niedobór alfa1-antytrypsyny
@pl
عوز ألفا1 أنتيتريبسين
@ar
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Alpha-1 antitrypsin deficiency
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