Antioch is a ghost town in Sheridan County, Nebraska, United States. Located approximately 15 miles east of Alliance on Nebraska Highway 2, the town was once nicknamed "the potash capital of Nebraska." The town took its name from Antioch, Ohio. The location of the town near several major alkali lakes among the Sandhills of western Nebraska made Antioch the logical home of five potash reduction factories: the American, Nebraska, Alliance, National, and Western potash companies. All these companies were major suppliers of potash during World War I.