Azathioprine
Azathioprine (AZA), also known by its brand name Imuran, is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues. Synthesized originally as a cancer drug and a prodrug for mercaptopurine in 1957, it has been widely used as an immunosuppressant for more than 50 years. Azathioprine is produced by a number of manufacturers under different brand names. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
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Azathioprine
Azathioprine (AZA), also known by its brand name Imuran, is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues. Synthesized originally as a cancer drug and a prodrug for mercaptopurine in 1957, it has been widely used as an immunosuppressant for more than 50 years. Azathioprine is produced by a number of manufacturers under different brand names. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
has abstract
25بك المحتوى هنا ينقصه الاستشه ...... via and France, among others).
@ar
A azatioprina é um análogo sin ...... metabolizada por três enzimas.
@pt
Azathioprin ist ein Arzneistof ...... der Immunreaktion einhergehen.
@de
Azathioprine (AZA), also known ...... eded in a basic health system.
@en
Azathioprine is een Immuunsupp ...... inogeen voor mensen (groep 1).
@nl
Azatiopryna (łac. Azathioprinu ...... ą. Bywa też podawana dożylnie.
@pl
L'azathioprine, 6-(1-méthyl-4- ...... actif est la 6-mercaptopurine.
@fr
La azatioprina es un profármac ...... es de riñón, corazón e hígado.
@es
L’azatioprina è un principio a ...... no un elevato indice mitotico.
@it
Азатиоприн — лекарственное сре ...... нейших лекарственных средств».
@ru
ATC prefix
ATC suffix
Bioavailability
CAS number
CAS supplemental
(sodiumsalt)
DrugBank
FDA UNII code
MRK240IY2L
IUPAC name
6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
@en
PubChem
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Link from a Wikipage to an external page
Wikipage page ID
Wikipage revision ID
738,191,575
ChEMBL
ChemSpiderID
elimination half-life
excretion
Renal, 98% as metabolites
legal CA
legal US
licence US
MedlinePlus
melting high
melting point
metabolism
Activated non-enzymatically, deactivated mainly by xanthine oxidase
molecular weight
2.77263e+2
protein bound
routes of administration
smiles
[O-][N+]c3ncnC
StdInChIKey
LMEKQMALGUDUQG-UHFFFAOYSA-N
tradename
Azasan, Imuran and others
verifiedrevid
458,437,709