The Babcock Block was a historic commercial building at 600 Main Street in Worcester, Massachusetts. Built in the 1860s, it was a rare example of granite construction in the period. The Main Street facade of the five story building was constructed out of granite blocks, while that facing Austin Street was of pressed brick. Chester Babcock, its first recorded owner, was a mover of buildings. The building was listed on the National Register of Historic Places in 1980. It was demolished to make way for construction of the Sky Mark Tower.