Belatacept
Belatacept (trade name Nulojix) is a fusion protein composed of the Fc fragment of a human IgG1 immunoglobulin linked to the extracellular domain of CTLA-4, which is a molecule crucial in the regulation of T-cell costimulation, selectively blocking the process of T-cell activation. It is intended to provide extended graft survival while limiting the toxicity generated by standard immune suppressing regimens, such as calcineurin inhibitors. It differs from abatacept (Orencia) by only 2 amino acids.
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Belatacept
Belatacept (trade name Nulojix) is a fusion protein composed of the Fc fragment of a human IgG1 immunoglobulin linked to the extracellular domain of CTLA-4, which is a molecule crucial in the regulation of T-cell costimulation, selectively blocking the process of T-cell activation. It is intended to provide extended graft survival while limiting the toxicity generated by standard immune suppressing regimens, such as calcineurin inhibitors. It differs from abatacept (Orencia) by only 2 amino acids.
has abstract
Belatacept (trade name Nulojix ...... ministration on June 15, 2011.
@en
Belatacept – lek biologiczny o ...... zawierającego lek to Nulojix.
@pl
Belatacepte (nome comercial: N ...... rtence a Bristol-Myers Squibb.
@pt
Le bélatacept est une molécule utilisée comme médicament immunosuppresseur.
@fr
ATC prefix
ATC suffix
FDA UNII code
E3B2GI648A
Wikipage page ID
Wikipage revision ID
738,458,460
ChemSpiderID
legal US
licence US
MedlinePlus
routes of administration
tradename
Verifiedfields
verifiedrevid
447,616,853
hypernym
comment
Belatacept (trade name Nulojix ...... rencia) by only 2 amino acids.
@en
Belatacept – lek biologiczny o ...... zawierającego lek to Nulojix.
@pl
Belatacepte (nome comercial: N ...... rtence a Bristol-Myers Squibb.
@pt
Le bélatacept est une molécule utilisée comme médicament immunosuppresseur.
@fr
label
Belatacept
@en
Belatacept
@pl
Belatacepte
@pt
Bélatacept
@fr