Bis-choline tetrathiomolybdate
Bis-choline tetrathiomolybdate (or tiomolibdate USAN, trade name Decuprate), is a salt of tetrathiomolybdate (TTM, MoS42−) and choline currently under investigation as a therapy against Wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. Wilson's disease is an autosomal recessive genetic disorder that is manifested by serious hepatic, neurologic or psychiatric symptoms. The disease is fatal if left undiagnosed and untreated. It is estimated that approximately 1 individual in every 30,000 worldwide have Wilson's disease, corresponding to approximately 15,000 individuals in the European Union and approximately 11,000 in the United States.
primaryTopic
Bis-choline tetrathiomolybdate
Bis-choline tetrathiomolybdate (or tiomolibdate USAN, trade name Decuprate), is a salt of tetrathiomolybdate (TTM, MoS42−) and choline currently under investigation as a therapy against Wilson's disease, a rare and potentially fatal disease in which the body cannot regulate copper. Wilson's disease is an autosomal recessive genetic disorder that is manifested by serious hepatic, neurologic or psychiatric symptoms. The disease is fatal if left undiagnosed and untreated. It is estimated that approximately 1 individual in every 30,000 worldwide have Wilson's disease, corresponding to approximately 15,000 individuals in the European Union and approximately 11,000 in the United States.
has abstract
Bis-choline tetrathiomolybdate ...... founded by HealthCap in 2012.
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Wikipage page ID
42,700,966
Wikipage revision ID
731,745,842
ATC prefix
CAS number
ChemSpiderID
19,906,891
DrugBank
legal status
Investigational
molecular weight
4.32542e+2
PubChem
18,442,052
smiles
OCC[N+]C.[S-][Mo]=S.C[N+]CCO
StdInChIKey
NEYVHGQOGHJAAD-UHFFFAOYSA-N
synonyms
Choline tetrathiomolybdate; ATN-224; WTX101
tradename
subject
hypernym
comment
Bis-choline tetrathiomolybdate ...... y 11,000 in the United States.
@en
label
Bis-choline tetrathiomolybdate
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