The Brigham House is a historic house at 235 Main Street in Waltham, Massachusetts. The 2-1/2 story wood frame house was built c. 1893, and is an architecturally distinctive hybrid of Queen Anne, Shingle, and Colonial Revival styling. It has the asymmetrical appearance and irregular roof lines typical of Queen Anne styling, but the elements assembled in that manner are predominantly Colonial Revival and Shingle. A central projecting section with a hip roof has an extended eave with modillions, and windows with diamond lights. The left side of the main facade has a roof line that descends to the first floor, with a bell-shaped gable dormer. A Colonial Revival entry porch projects from a left-of-center position; it is enclosed in paned glass, but has square corner pillars.