COPP (chemotherapy)
COPP is a chemotherapy regimen for treatment of Hodgkin disease, consisting of concurrent treatment with (C)yclophosphamide, (O)ncovin, (P)rocarbazine and (P)rednisone. It contains less procarbazine than MOPP (procarbazine is given only for 10 days in cycle instead of 14), and the very toxic mechlorethamine, which is prone to give severe neutropenia and to severely heighten the risk of secondary malignancies, is changed to less toxic cyclophosphamide, which is more safe to the progenitor stem cells (thus, less neutropenia) and less prone to give late secondary malignancies.
COPP (chemotherapy)
COPP is a chemotherapy regimen for treatment of Hodgkin disease, consisting of concurrent treatment with (C)yclophosphamide, (O)ncovin, (P)rocarbazine and (P)rednisone. It contains less procarbazine than MOPP (procarbazine is given only for 10 days in cycle instead of 14), and the very toxic mechlorethamine, which is prone to give severe neutropenia and to severely heighten the risk of secondary malignancies, is changed to less toxic cyclophosphamide, which is more safe to the progenitor stem cells (thus, less neutropenia) and less prone to give late secondary malignancies.
has abstract
COPP (латиницей) — общепринята ...... преимущество в эффективности.
@ru
COPP is a chemotherapy regimen ...... tive than either COPP or MOPP.
@en
Unter dem COPP-Schema versteht ...... d.h. Tag 29 entspricht Tag 1.
@de
Wikipage page ID
Wikipage revision ID
626,053,030
hypernym
comment
COPP (латиницей) — общепринята ...... преимущество в эффективности.
@ru
COPP is a chemotherapy regimen ...... e late secondary malignancies.
@en
Unter dem COPP-Schema versteht ...... d.h. Tag 29 entspricht Tag 1.
@de
label
COPP (chemotherapy)
@en
COPP
@ru
COPP-Schema
@de