The Cancionero de la Colombina or Cancionero Musical de la Colombina (CMC) is a Spanish manuscript (Ms. 7-1-28) containing Renaissance music from the second half of the 15th century. The manuscript was copied during the reign of the Catholic Monarchs, possibly between the 1460s and the 1480s. Therefore, it predates the more famous Cancionero de Palacio. The first half of the manuscript is the work of two main scribes, and the second half was completed by six other scribes. It originally comprised 106 folios, 8 of which are lost. The general condition of the remaining folios is less than satisfactory. A title added on a later period reads "Cantilenas vulgares puestas en musica por varios Españoles" (Popular melodies set to music by various Spaniards).