Cyclol
The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late 1930s, and was based on three assumptions. Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. These reactions have been observed in the ergopeptides and other compounds. Secondly, it assumes that, under some conditions, amino acids will naturally make the maximum possible number of cyclol crosslinks, resulting in cyclol molecules (Figure 2) and cyclol fabrics (Figure 3). These cyclol molecules and fabrics have never been observed. Finally, the hypothesis assumes that globular proteins have a tertiary structure corr
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Cyclol
The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late 1930s, and was based on three assumptions. Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. These reactions have been observed in the ergopeptides and other compounds. Secondly, it assumes that, under some conditions, amino acids will naturally make the maximum possible number of cyclol crosslinks, resulting in cyclol molecules (Figure 2) and cyclol fabrics (Figure 3). These cyclol molecules and fabrics have never been observed. Finally, the hypothesis assumes that globular proteins have a tertiary structure corr
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L'hypothèse du cyclol est le p ...... chimie Portail de la biochimie
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La hipótesis del ciclol es una ...... o parte del método científico.
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The cyclol hypothesis is the f ...... part of the scientific method.
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Гипотеза цикло́лов — первая ст ...... труктуры также не наблюдаются.
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فرضية السيكلول هوأول النموذج ا ...... "جزيئات المغلقة لسيكلول" سواء.
@ar
环醇假说(cyclol hypothesis),為第一个折叠 ...... 测试也为经验证伪性作为科学方法的一部分提供了一个很好的例证。
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L'hypothèse du cyclol est le p ...... chimie Portail de la biochimie
@fr
La hipótesis del ciclol es una ...... bservadas. Finalmente, la hipó
@es
The cyclol hypothesis is the f ...... have a tertiary structure corr
@en
Гипотеза цикло́лов — первая ст ...... реакции образования циклолов.
@ru
فرضية السيكلول هوأول النموذج ا ...... سيج سيكلول مع عدم وجود حواف ال
@ar
环醇假说(cyclol hypothesis),為第一个折叠 ...... 测试也为经验证伪性作为科学方法的一部分提供了一个很好的例证。
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Cyclol
@en
Cyclol
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Hipótesis del ciclol
@es
Циклолы
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سيكلول
@ar
环醇假说
@zh