"Disease" was released on September 30, 2002 as the first single from Matchbox Twenty's third album, More Than You Think You Are. It was co-written by Matchbox Twenty lead singer Rob Thomas and The Rolling Stones frontman Mick Jagger. The song peaked at #29 on the Billboard Hot 100. "Disease" was one of two songs written and presented to Mick Jagger, by Rob Thomas in which Jagger actually gives back the song, saying "it would sound better coming from you".