Djedkare Isesi (known in Greek as Tancherês) was an Ancient Egyptian pharaoh, the eighth and penultimate ruler of the Fifth Dynasty in the late 25th century to mid 24th century BCE, during the Old Kingdom period. Djedkare succeeded Menkauhor Kaiu and was in turn succeeded by Unas. His relations to both of these pharaohs remain uncertain, although it is often conjectured that Unas was Djedkare's son owing to the smooth transition between the two.