Embutramide
Embutramide (INN, USAN, BAN) (brand name Embutane) is a potent opioid analgesic and sedative drug that is structurally related to methadone. It was developed by Hoechst A.G. in 1958 and was investigated as a general anesthetic agent, but was found to have a very narrow therapeutic window, with a 50 mg/kg dose producing effective sedation and a 75 mg/kg dose being fatal. Along with strong sedative effects, embutramide also produces respiratory depression and ventricular arrhythmia. Because of these properties, it was never been adopted for medical use as an anesthetic as it was considered too dangerous for this purpose. Instead it is used for euthanasia in veterinary medicine, mainly for the euthanization of dogs.
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Embutramide
Embutramide (INN, USAN, BAN) (brand name Embutane) is a potent opioid analgesic and sedative drug that is structurally related to methadone. It was developed by Hoechst A.G. in 1958 and was investigated as a general anesthetic agent, but was found to have a very narrow therapeutic window, with a 50 mg/kg dose producing effective sedation and a 75 mg/kg dose being fatal. Along with strong sedative effects, embutramide also produces respiratory depression and ventricular arrhythmia. Because of these properties, it was never been adopted for medical use as an anesthetic as it was considered too dangerous for this purpose. Instead it is used for euthanasia in veterinary medicine, mainly for the euthanization of dogs.
has abstract
Embutramid ist ein stark betäu ...... hanasie) von Tieren verwendet.
@de
Embutramide (INN, USAN, BAN) ( ...... and other sedative-hypnotics..
@en
L'embutramide est un anesthési ...... mercialisé sous le nom de T61.
@fr
ATC prefix
CAS number
15687-14-6
DrugBank
FDA UNII code
3P4TQG94T1
IUPAC name
N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxybutanamide
@en
PubChem
thumbnail
Wikipage page ID
14,624,054
Wikipage revision ID
742,111,008
ChemSpiderID
legal US
molecular weight
2.93401e+2
routes of administration
StdInChIKey
LMBMDLOSPKIWAP-UHFFFAOYSA-N
verifiedrevid
448,000,423
comment
Embutramid ist ein stark betäu ...... hanasie) von Tieren verwendet.
@de
Embutramide (INN, USAN, BAN) ( ...... for the euthanization of dogs.
@en
L'embutramide est un anesthési ...... mercialisé sous le nom de T61.
@fr
label
Embutramid
@de
Embutramide
@en
Embutramide
@fr