Giovanni J. Ughi (born Padova, Italy), Italian engineer and scientist, is one of the inventors of multimodality Optical Coherence Tomography (OCT) and Laser-induced fluorescence molecular imaging, pioneering a first-in-man study of coronary arteries during his work at Massachusetts General Hospital. The results of his work, combining two imaging technologies, may better identify dangerous coronary plaques, responsible for coronary artery disease and myocardial infarction. He also was one of the pioneers of targeted molecular imaging of human atherosclerosis, determining the use of an FDA approved molecular agent (i.e., indocyanine green (ICG)-enhanced near-infrared fluorescence) that can illuminate high-risk features of human carotid atherosclerosic plaques and other molecular agents for t