Glycol nucleic acid
Glycol nucleic acid (GNA) is a polymer similar to DNA or RNA but differing in the composition of its "backbone". GNA is not known to occur naturally; they are synthesized chemically. The 2,3-dihydroxypropylnucleoside analogues were first prepared by Ueda et al. (1971). Soon thereafter it was shown that phosphate-linked oligomers of the analogues do in fact exhibit hypochromicity in the presence of RNA and DNA in solution (Seita et al. 1972). The preparation of the polymers was later described by Cook et al. (1995, 1999) and Acevedo and Andrews (1996). The GNA-GNA self-pairing described by Zhang and Meggers is however novel, and the specificity of interaction well-demonstrated.
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Glycol nucleic acid
Glycol nucleic acid (GNA) is a polymer similar to DNA or RNA but differing in the composition of its "backbone". GNA is not known to occur naturally; they are synthesized chemically. The 2,3-dihydroxypropylnucleoside analogues were first prepared by Ueda et al. (1971). Soon thereafter it was shown that phosphate-linked oligomers of the analogues do in fact exhibit hypochromicity in the presence of RNA and DNA in solution (Seita et al. 1972). The preparation of the polymers was later described by Cook et al. (1995, 1999) and Acevedo and Andrews (1996). The GNA-GNA self-pairing described by Zhang and Meggers is however novel, and the specificity of interaction well-demonstrated.
has abstract
Pour les articles homonymes, ...... es de vies apparues sur Terre.
@fr
El ácido nucleico glicólico es ...... les ácidos nucleicos. Ver más.
@es
GNA全名Glycerol nucleic acid,中文直 ...... NA的鹼基配對更為穩定,需要較高的融解溫度(Tm)才能解開。
@zh
Glikolowy kwas nukleinowy (GNA ...... sów nukleinowych, DNA czy RNA.
@pl
Glycol nucleic acid (GNA) is a ...... hypothetical precursor to RNA.
@en
グリコール核酸(Glycol nucleic acid、GN ...... 最も単純な構造であるため、RNAの先駆けとも考えられている。
@ja
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Pour les articles homonymes, ...... les naturelles d'ARN et d'ADN.
@fr
El ácido nucleico glicólico es ...... les ácidos nucleicos. Ver más.
@es
GNA全名Glycerol nucleic acid,中文直 ...... NA的鹼基配對更為穩定,需要較高的融解溫度(Tm)才能解開。
@zh
Glikolowy kwas nukleinowy (GNA ...... sów nukleinowych, DNA czy RNA.
@pl
Glycol nucleic acid (GNA) is a ...... interaction well-demonstrated.
@en
グリコール核酸(Glycol nucleic acid、GN ...... 最も単純な構造であるため、RNAの先駆けとも考えられている。
@ja
label
Acide nucléique à glycol
@fr
GNA
@zh
Glikolowy kwas nukleinowy
@pl
Glycol nucleic acid
@en
Ácido nucleico glicólico
@es
グリコール核酸
@ja