Hamilton railway station was one of several railway stations to serve the town of Hamilton, Scotland. It was opened on 1 April 1878 by the Glasgow, Bothwell, Hamilton and Coatbridge Railway. It was operated by the North British Railway, which under the Railways Act 1921 became part of the London and North Eastern Railway. The station was temporarily closed from 1 January 1917, reopening on 2 June 1919. Hamilton today is served by three stations on the Argyle Line. Services are provided by First ScotRail.