Inocoterone
Inocoterone (INN), or as inocoterone acetate (USAN) (developmental code names RU-882, RU-38882), also known as 17β-hydroxy-2,5-seco-A-dinorestr-9-en-5-one [acetate], is a non-steroidal antiandrogen that was developed in 1985 for topical administration but was never marketed. It was investigated for the treatment of acne but showed only modest (albeit statistically significant) efficacy in clinical trials. A reduction of 26% of lesions was observed in males treated with the drug after 16 weeks (~3.7 months). However, this is notably far less than that achieved with other agents such as benzoyl peroxide or antibiotics, which produce 50–75% reductions within 2 months. Similar poor results with the topical route have disappointingly been found for other antiandrogens such as cyproterone acetat
Wikipage redirect
primaryTopic
Inocoterone
Inocoterone (INN), or as inocoterone acetate (USAN) (developmental code names RU-882, RU-38882), also known as 17β-hydroxy-2,5-seco-A-dinorestr-9-en-5-one [acetate], is a non-steroidal antiandrogen that was developed in 1985 for topical administration but was never marketed. It was investigated for the treatment of acne but showed only modest (albeit statistically significant) efficacy in clinical trials. A reduction of 26% of lesions was observed in males treated with the drug after 16 weeks (~3.7 months). However, this is notably far less than that achieved with other agents such as benzoyl peroxide or antibiotics, which produce 50–75% reductions within 2 months. Similar poor results with the topical route have disappointingly been found for other antiandrogens such as cyproterone acetat
has abstract
Inocoterone (INN), or as inoco ...... ne acetate and spironolactone.
@en
CAS number
83646-97-3
CAS supplemental
83646-86-0 (acetate)
FDA UNII code
Q35F31B844
IUPAC name
(3S,3aS,9aS,9bS)-6-Ethyl-3-hyd ...... -cyclopenta[a]naphthalen-7-one
@en
PubChem
thumbnail
Wikipage page ID
41,568,202
Wikipage revision ID
742,344,264
ChemSpiderID
molecular weight
2.4836056e+2
routes of administration
smiles
StdInChIKey
DOTDLCMVUVGSDP-VRKREXBASA-N
hypernym
comment
Inocoterone (INN), or as inoco ...... ens such as cyproterone acetat
@en
label
Inocoterone
@en