Johannes Megapolensis (1603–1670) was a dominie (pastor) of the Dutch Reformed Church in the Dutch colony of New Netherland (present-day New York state in the United States), beginning in 1642. Serving for several years at Fort Orange (present-day Albany, New York) on the upper Hudson River, he is credited with being the first Protestant missionary to the Indians in North America. He later served as a minister in Manhattan, staying through the takeover by the English in 1664.