John Holmes House, also known as the Cresse-Holmes House, is located in the Cape May Court House section of Middle Township, Cape May County, New Jersey, United States. The house was originally thought to be built in 1755 and was added to the National Register of Historic Places on June 12, 1979. Later research has shown the date of the oldest part of the house to be 1704, built by John Cresse. The "newer" portion of the house was built by Robert Morris Holmes, son of John Holmes, in 1830.