The Journal des sçavans (later renamed Journal des savants), established by Denis de Sallo, was the earliest academic journal published in Europe. Its content included obituaries of famous men, church history, and legal reports. The first issue appeared as a twelve-page quarto pamphlet on Monday, 5 January 1665. This was shortly before the first appearance of the Philosophical Transactions of the Royal Society, on 6 March 1665. The 18th-century French physician and encyclopédiste Louis-Anne La Virotte (1725–1759) was introduced to the journal through the protection of chancellor Henri François d'Aguesseau.